Members’ pick for journal club

The Laboratory of
Vascular Health and Disease

Members’ pick for journal club

Members’ pick for journal club



Jan Hae Young:

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.

2022 Cell 185, 2213-2233



DecSeung Eun:

A single-cell atlas of the normal and malformed human brain vasculature. 

2022 Science 375, eabi7377  

Sep, Hae Young, Melissa, and Hyeon Jin:   

Analysis of peer reviewers' comments   

Aug, Seong Woo:

Glioblastoma hijacks neuronal mechanisms for brain invasion 

2022 Cell 185, 2899

July, Seung Eun:

Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood-brain barrier in acute 

ischemic stroke. 2022 Acta Neuropathologica 144, 305


JuneHae Young:

Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during 

angiogenesis2022 Developmental Cell 57, 1


Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin. 

2015 The Journal of Experimental Medicine 13, 2267

Mar, Melissa:

Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intratumoral heterogeneity. 

2022 Nature Communications 13, 116

Feb, Seong Woo:

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy. 

2020 Nature communication 11, 3406

Jan, Seung Eun:

Non-productive angiogenesis disassembles Ab plaque-associated blood vessels. 

2021 Nature Communications 12, 3098




Nov, Haemin:

Cell lineage-based stratification for glioblastoma. 2020 Cancer Cell 38, 366-379


Dec, Hae Young:

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition. 2021 Cell Metabolism 33, 818-832